The Most Delicious Gluten-Free Meatloaf Recipe

Updated on March 20, 2018

Can a meatloaf be gluten-free?

Absolutely! This unbelievably delicious meatloaf also happens to be gluten-free. This is my celiac-friendly version of a recipe I originally discovered on Alton Brown’s cooking show, Good Eats. This recipe has been modified to include pork as well as beef and has two breadcrumb substitution options.

It’s easy. It’s homey. It’s delicious.

Let's make it!

Cook Time

Prep time: 20 min
Cook time: 55 min
Ready in: 1 hour 15 min
Yields: Serves four people


  • 1 lb ground beef
  • 1 lb ground pork
  • 1 1/2 tsp salt
  • 1 tsp dried thyme
  • 1/2 tsp freshly ground pepper, cracked
  • 1 egg
  • 1 onion, minced
  • 2 cups white mushrooms, finely chopped or 1 cup gluten-free breadcrumbs
  • 1 tbsp butter
  • 1 tsp red chile pepper flakes/powder
  • 1/2 tsp oregano
  • 3 garlic cloves, minced
  • 1/2 cup ketchup
  • 1 tbsp honey
  • Dash of Tabasco and Worcestershire (Worcestershire may contain gluten. Check and omit if desired)


  1. Preheat the oven to 350° F.
  2. Heat the butter in a medium skillet and saute the mushrooms until they're softened, which takes around two to three minutes. The mushrooms replace the breadcrumbs, making the loaf gluten-free and keeping it from getting too dense.
  3. In a bowl, mix the two meats, herbs, egg, onion, garlic, salt, pepper, and the mushrooms. If you're not using mushrooms, substitute it with one cup of gluten-free breadcrumbs.
  4. Mix everything well, and test the seasoning by taking a small amount of the meat mixture and microwaving it until it's cooked. Taste it and adjust hte seasonings to your taste. This is an easy step that ensures you didn't forget an ingredient.
  5. Pat the meat into a loaf pan. Place a little parchment paper or foil on a baking sheet. Invert the loaf pan onto the parchment paper. Tap the bottom of the loaf pan with a knife before you lift it away to ensure your loaf slides out cleanly onto the paper.
  6. Place the meatloaf into the oven for 10-15 minutes.
  7. Mix the ketchup, honey, hot sauce, and Worcestershire together.
  8. After 10-15 minutes, remove the meatloaf from the oven and glaze it with the mixture you just created. Put it back in the oven and cook until an instant-read thermometer reads 150°F when inserted in the deepest interior of the loaf. This should take about 40 minutes.
  9. You're done! This tastes so very good.

Questions & Answers


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      • profile image

        Iliana 3 years ago

        Second time making this recipe but used gf bread crumbs. My family loved it so much the first time, that I'm making two that's in the oven right now!

        Thanks for sharing!

      • profile image

        Kevin 4 years ago

        Another good substitute I've found for the binding agent, instead of bread crumbs, that can offer a nice texture and flavor is instant mashed potato flakes. Can even use the flavored ones (garlic and cheese are both nice options)

      • profile image

        Kathymom 5 years ago

        Unless noted condiments made with "vinegar" use White Vinegar and white vinegar is made from wheat. So anyone with a gluten or wheat intolerance would be sensitive to these. You can find ketchup, mustard, mayo, pickles, etc made with apple cider vinegar.

        I am looking forward to trying this with these adjustments. Thanks.

      • profile image

        Katie 5 years ago

        This is our favorite meatloaf recipe of all time! My boyfriend is allergic to dairy as well as gluten, so I substitute Earth Balance or olive oil when sautéing the mushrooms. Other than that, this recipe is perfect for us and is a regular favorite served with garlic mashed potatoes and green beans. The flavor of the mushrooms is not obviouse like I thought it might be the first time I made it, it give the loaf a nice, moist texture and is a clever substitute for breadcrumbs.

        Thanks for sharing!!

      • profile image

        Sandy Franklin 5 years ago

        Just made this for my neighbor. We all loved it. The best meatloaf we've had!

      • profile image

        kate t 5 years ago

        I just made this ; yummy! The Worcestire sauce I used IS gluten free, Lea & perrins (or Perrons). Thank you!

      • profile image

        Jayne 5 years ago

        Dammm! Excellent! I tweaked it to suit me -- more veggies and less meat. I used maybe 9/10 lb grass-fed ground beef and no pork. I cut the salt to maybe 1/2 tsp and upped the oregano and added parsley. I didn't bother sauteing the mushrooms first, just threw them in the bowl along with everything else. I also added about 1-1/2 c grated zucchini and 1 c (packed) carrot pulp. I omitted the butter, pepper flakes and glaze; simply served with organic ketchup. Awesome!

      • profile image

        TaraMashell 5 years ago

        Oh wow, thanks so much for this receipe. I had just made a meatlof the other day by using Shar's gluten free bread crumbs, and I didn't like it very well. As a matter-of-fact, I only ate a couple of slices and wrapped the remainder amount & placed it in the freezer. I would have never thought to use white mushrooms as a binder. I'm also not suppose to have yeast either, so I really shouldn't have used the bread crumbs anyway. A couple of commenters' uptop had a few good ideas as well; adding cornbread & quinoa (which I have yet to try) sounds ideal, too. Thanks again! Will try this out this week. Oh yeah, finally a meatloaf receipe that doesn't call for worcestershire sauce. Man I can't stand that stuff, LOL.

      • profile image

        kathy 5 years ago

        I had heard the Lee and Perrins is gluten free if u purchase the one made in USA and not Canada

      • profile image

        AlldaveAllthetime 6 years ago

        Lee and Perins is gluten free.

      • John D Lee profile image

        John D Lee 6 years ago

        Thanks Cynthia - I'll make a note of that in the text.

      • profile image

        Alyssa Nebel 6 years ago

        worcestershire is not gluten free!!!

      • profile image

        GinaBObeeena 6 years ago

        Thanks for the delicious recipe! I was craving meat loaf and this was so yummi, everyone LOVED it. I think the sauce is really delicious, and totally curbed my craving. I will be making this on a regular basis... thanks again!

      • profile image

        Cynthia 6 years ago

        True Celiac's need to be careful of the Worchestershire sauce in this recipe as it has gluten in it - a trace amount, but that could be enough to affect a very sensitive Celiac.

      • profile image

        Paula 6 years ago

        I just made this, and yes, it is GOOD. I formed it into a Mummy Meatloaf for Halloween! Thank you for the inspiration :)

      • bettybarnesb profile image

        bettybarnesb 7 years ago from Bartlett, TN

        I love meatloaf. So does my family. Enjoyed your hub

      • profile image

        Jenn, The Gluten Free Connoisseur 7 years ago

        Thanks for this awesome recipe! It is snowing again outside and I wanted a nice comfort food so I made this tonight and LOVED it! My husband is a huge meatloaf fan and I have made other gf recipes in the past but this one definitely is the BEST we have had. I did however change the ground pork to thinly sliced german sausage which added another bit of spice. I always make a big batch of gf breadcrumbs so I had that on hand tonight.

        On the gf oats topic... I have been on a gf diet for almost 11 years now and could not tolerate any type of oats so I just never ate them until recently. I'm able to get Bob's Red Mill gf oats at our store here in Germany and eat them every morning with no problems! I truly believe that the gf oats are safe for a celiac.

        Thanks again!! If you don't mind I would like to post your recipe on my blog as well.

      • infonolan profile image

        infonolan 7 years ago from Australia

        Oats contain avenin, which indeed is under investigation at this point in time as to how much gluten is contained here. Laws differ from country to country and for a product to be legally labelled 'gluten free' here in Australia, it cannot legally contain oats or oat derivatives in any form. In other words, it is quite probable that there is no such thing as 'gluten free' oats.

        My hub illustrates the limitations behind this process.

      • profile image

        Angela 7 years ago

        I am on a gluten free diet and can't have oatmeal. I can have Buckwheat however. Also for those with inflamation problems avoid corn and dairy also.

      • profile image

        Lolo 7 years ago

        Bob's Red Mill produces a certified gluten free oatmeal product, so it would be safe to use. I had heard that Quaker Oats oatmeal has gluten in it because it is produced in a factory with wheat products and as a result it may have quite a bit of cross contamination.

      • profile image

        Ashley 7 years ago

        Some people who can't have gluten can't have oatmeal either.

      • profile image

        candy 7 years ago

        cornbread crumbs taste better

      • John D Lee profile image

        John D Lee 7 years ago

        Thanks Candy - I had this meatloaf for dinner earlier in the week myself - always a favorite with my family as well.

      • profile image

        Candy 7 years ago

        LOVE this recipe! It has become a favorite at my house. Thanks for the idea. Wonderful treat! I hope posed it on my blog. Thanks!

      • John D Lee profile image

        John D Lee 7 years ago

        Matt, thank you also for your tip!

      • profile image

        Matt 7 years ago

        You can also use Oatmeal as a binding for meatloaf to make it Gluten-Free.

      • John D Lee profile image

        John D Lee 7 years ago

        Hi Jennifer,

        Thanks very much for the tip - sounds great!

      • Jennifer profile image

        Jennifer 7 years ago

        I made my last meatloaf with leftover quinoa rather than breadcrumbs and it was delicious. It is also gluten free.

      • askjanbrass profile image

        askjanbrass 8 years ago from St. Louis, MO

        This looks like a great recipe for gluten free meatloaf. I have some friends who can't have gluten, so I'm always very conscious of that when I have them over for dinner. I think I will make this next time they come.

        Thanks for sharing!

      • John D Lee profile image

        John D Lee 8 years ago

        Hi JT,

        Thanks for the warning about worcestershire.

      • profile image

        jt 8 years ago

        For people that aren't used to cooking gluten-free, and might be making it for a celiac friend, it should be noted that the most popular brands of worcestershire sauce are *not* gluten free! (contains barley malt) Make sure you're buying a gluten free version of the sauce!

      • nikki1 profile image

        nikki1 8 years ago

        LOve meat loaf/ great share : )

      • Leenie Pooh profile image

        Leenie Pooh 8 years ago

        Thank you so much. I practice food combining (as much as possible) so meatloaf has been off my menu for awhile as I couldn't think of what to use in place of breadcrumbs. I suppose the mushrooms work because they tend to absorb water.

      • june688 profile image

        june688 8 years ago

        This is good and I like it.

      • dohn121 profile image

        dohn121 8 years ago from Hudson Valley, New York

        What a great idea, John! Thanks again.